在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Bovine Mothers against decapentaplegic homolog 4 (SMAD4), partial

Recombinant Bovine Mothers against decapentaplegic homolog 4 (SMAD4), partial

  • 中文名稱：
    牛SMAD4重組蛋白
  • 貨號(hào)：
    CSB-YP627061BO
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    牛SMAD4重組蛋白
  • 貨號(hào)：
    CSB-EP627061BO
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    牛SMAD4重組蛋白
  • 貨號(hào)：
    CSB-EP627061BO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    牛SMAD4重組蛋白
  • 貨號(hào)：
    CSB-BP627061BO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    牛SMAD4重組蛋白
  • 貨號(hào)：
    CSB-MP627061BO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    SMAD4; Mothers against decapentaplegic homolog 4; MAD homolog 4; Mothers against DPP homolog 4; SMAD family member 4; SMAD 4; Smad4
  • 種屬：
    Bos taurus (Bovine)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in response to TGF-beta. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions. May act as a tumor suppressor. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8.
  • 基因功能參考文獻(xiàn)：
    1. Data suggest SMAD4 mRNA is increased in oocytes during maturation, is maximal in 2-cell blastocysts, remains elevated through 8-cell stage, and is decreased in remaining ectogenesis; embryotrophic actions of follistatin are SMAD4 dependent. PMID: 25031360
    2. ALK5 and Smad4 have roles in TGF-beta1-induced pulmonary endothelial permeability PMID: 16004987
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Dwarfin/SMAD family
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 精品国产乱码久久久久久下载| 国产亚洲成av片在线观看| 换脸国产av一区二区三区| 久久99亚洲精品久久久久| 99精品国产一区二区三区不卡 | 一区一区三区产品乱码| 少妇扒开粉嫩小泬视频| 国产真实交换配乱婬95视频| 高清av熟女一区| 久久久免费无码成人影片 | 爆爽久久久一区二区又大又黄又嫩| 午夜亚洲乱码伦小说区69堂| 亚洲欧美日韩另类丝袜一区| 亚洲成av人片在www色猫咪| 啦啦啦中文在线观看日本| 欧亚乱熟女一区二区三区在线| 婷婷色五月开心五月| 日本一区二区在线播放| 欧洲熟妇色xxxx欧美老妇老头多毛| 日本人妻中文字幕乱码系列| 99在线精品视频观看免费| 十八禁裸体www网站免费观看| 亚洲综合av色婷婷| 久久这里只有是精品23| 久久综合九色综合97欧美| 久久综合88熟人妻| 午夜福利视频极品国产83| 暴力强奷在线播放无码| 国产高清在线a视频大全| 国产又色又爽又黄的在线观看视频| 手机看片精品国产福利| 亚洲人成网网址在线看| 人人妻人人澡人人爽国产一区| 女m羞辱调教视频网站| 熟妇高潮一区二区三区| 久久人人妻人人做人人爽| 中文字幕在线亚洲二区| 国产精品自在在线午夜免费| 88国产精品视频一区二区三区| 亚洲伊人久久大香线蕉综合图片| 亚洲人成小说网站色在线观看|